3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside

Names

[ Name ]:
3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside

Biological Activity

[Description]:

3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₂₃ClN₄O₅

[ Molecular Weight ]:
506.94

[ Exact Mass ]:
506.13600

[ PSA ]:
105.43000

[ LogP ]:
4.46660

3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream