mosapramine

Names

[ CAS No. ]:
89419-40-9

[ Name ]:
mosapramine

[Synonym ]:
Mosapramine (INN)
Mosapramine
Mosapramine HCl
Spiro[imidazo[1,2-a]pyridine-3(2H),4'-piperidin]-2-one,1'-[3-(3-chloro-10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]hexahydro
1'-[3-(3-chloro-10,11-dihydro-5h-dibenzo[b,f]azepin-5-yl)propyl]hexahydro-2h-spiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one

Biological Activity

[Description]:

Mosapramine (Clospipramine) is an orally active and potent dopamine receptor antagonist with high affinity to dopamine receptor subtypes 2, 3 and 4, and with moderate affinity for the 5-HT2 receptor. Mosapramine shows antipsychotic activity and can be used in schizophrenia research[1][2].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor
Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor
Research Areas >> Neurological Disease

Chemical & Physical Properties

[ Density]:
1.29g/cm3

[ Boiling Point ]:
680.2ºC at 760 mmHg

[ Molecular Formula ]:
C28H35ClN4O

[ Molecular Weight ]:
479.05700

[ Flash Point ]:
365.2ºC

[ Exact Mass ]:
478.25000

[ PSA ]:
38.82000

[ LogP ]:
5.01280

[ Index of Refraction ]:
1.666

[ Storage condition ]:
-20°C

Related Compounds