89419-40-9
89419-40-9 structure
- Name: mosapramine
- Chemical Name: 1'-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]spiro[1,5,6,7,8,8a-hexahydroimidazo[1,2-a]pyridine-3,4'-piperidine]-2-one
- CAS Number: 89419-40-9
- Molecular Formula: C28H35ClN4O
- Molecular Weight: 479.05700
- Catalog: API Nervous system medication Antipsychotic
- Create Date: 2018-07-12 20:25:13
- Modify Date: 2025-08-22 19:02:06
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Mosapramine (Clospipramine) is an orally active and potent dopamine receptor antagonist with high affinity to dopamine receptor subtypes 2, 3 and 4, and with moderate affinity for the 5-HT2 receptor. Mosapramine shows antipsychotic activity and can be used in schizophrenia research[1][2].
| Name | 1'-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]spiro[1,5,6,7,8,8a-hexahydroimidazo[1,2-a]pyridine-3,4'-piperidine]-2-one |
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| Synonyms |
Mosapramine (INN)
Mosapramine Mosapramine HCl Spiro[imidazo[1,2-a]pyridine-3(2H),4'-piperidin]-2-one,1'-[3-(3-chloro-10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]hexahydro 1'-[3-(3-chloro-10,11-dihydro-5h-dibenzo[b,f]azepin-5-yl)propyl]hexahydro-2h-spiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one |
| Description | Mosapramine (Clospipramine) is an orally active and potent dopamine receptor antagonist with high affinity to dopamine receptor subtypes 2, 3 and 4, and with moderate affinity for the 5-HT2 receptor. Mosapramine shows antipsychotic activity and can be used in schizophrenia research[1][2]. |
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| Related Catalog |
| Density | 1.29g/cm3 |
|---|---|
| Boiling Point | 680.2ºC at 760 mmHg |
| Molecular Formula | C28H35ClN4O |
| Molecular Weight | 479.05700 |
| Flash Point | 365.2ºC |
| Exact Mass | 478.25000 |
| PSA | 38.82000 |
| LogP | 5.01280 |
| Index of Refraction | 1.666 |
| Storage condition | -20°C |