Diethylcarbamic chloride
Names
[ CAS No. ]:
88-10-8
[ Name ]:
Diethylcarbamic chloride
[Synonym ]:
Carbamicchloride,diethyl
EINECS 201-798-5
MFCD00000636
diethylchloroformamide
N,N-diethylcarbamyl chloride
N,N-Diethylchloroformamide
Diethylcarbamyl chlo
diethylaminocarbonyl chloride
diethyl-carbamoylchlorid
N,N-diethylcarbamic acid chloride
diethyl-carbamicchlorid
Diethylaminoformyl chloride(D.E.C.C)
Diethylcarbamic chloride
diethylcarbamic acid chloride
Carbamic chloride, diethyl-
N,N-diethyl carbamoyl chloride
DECC
N,N-diethylaminocarbonyl chloride
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
186.0±9.0 °C at 760 mmHg
[ Melting Point ]:
−32 °C(lit.)
[ Molecular Formula ]:
C5H10ClNO
[ Molecular Weight ]:
135.592
[ Flash Point ]:
75.0±0.0 °C
[ Exact Mass ]:
135.045090
[ PSA ]:
20.31000
[ LogP ]:
1.30
[ Vapour Pressure ]:
0.7±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.446
[ Water Solubility ]:
HYDROLYSIS
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FD4025000
- CHEMICAL NAME :
- Carbamoyl chloride, diethyl-
- CAS REGISTRY NUMBER :
- 88-10-8
- BEILSTEIN REFERENCE NO. :
- 0506687
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C5-H10-Cl-N-O
- MOLECULAR WEIGHT :
- 135.61
- WISWESSER LINE NOTATION :
- GVN2&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2700 mg/kg
- TOXIC EFFECTS :
- Behavioral - coma Gastrointestinal - alteration in gastric secretion Blood - changes in spleen
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 159 ppm/7H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 12840 mg/kg
- TOXIC EFFECTS :
- Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5400 mg/kg/10D-I
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Related to Chronic Data - death
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 43200 mg/kg/72W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
- REFERENCE :
- JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(4),479,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY;Carcinogen JAN 1993
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H332-H335-H351
[ Precautionary Statements ]:
P261-P281-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R20/22;R36/37/38;R40
[ Safety Phrases ]:
S26-S36/37
[ RIDADR ]:
UN 3265 8/PG 3
[ WGK Germany ]:
1
[ RTECS ]:
FD4025000
[ Packaging Group ]:
II
[ Hazard Class ]:
8
[ HS Code ]:
2903199000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2903199000
[ Summary ]:
2903199000 other saturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
Toxicol. Eur. Res. 3(5) , 223-8, (1981)