Diethylcarbamazine
Names
[ CAS No. ]:
90-89-1
[ Name ]:
Diethylcarbamazine
[Synonym ]:
patonin
4-methyl-piperazine-1-carboxylic acid diethylamide
Caracide
84L
Caricide
Notezine
rp3799
Cypip
diethycarbamazine
Banocide
4-Methyl-piperazin-1-carbonsaeure-diaethylamid
Diethylcarbamazine
Ethodryl
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.013g/cm3
[ Boiling Point ]:
139ºC
[ Melting Point ]:
137 - 140ºC
[ Molecular Formula ]:
C10H21N3O
[ Molecular Weight ]:
199.29300
[ Flash Point ]:
98ºC
[ Exact Mass ]:
199.16800
[ PSA ]:
26.79000
[ LogP ]:
0.57140
[ Index of Refraction ]:
1.492
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TL1200000
- CHEMICAL NAME :
- 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-
- CAS REGISTRY NUMBER :
- 90-89-1
- BEILSTEIN REFERENCE NO. :
- 0143029
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C10-H21-N3-O
- MOLECULAR WEIGHT :
- 199.34
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 7300 mg/kg/1Y-I
- TOXIC EFFECTS :
- Skin and Appendages - dermatitis, allergic (after systemic exposure)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 240 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 630 mg/kg
- SEX/DURATION :
- female 7-11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 40 mg/kg
- REFERENCE :
- TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 44,7,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2728 No. of Facilities: 316 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 3161 (estimated) No. of Female Employees: 1581 (estimated)