Diphosgene
Names
[ CAS No. ]:
503-38-8
[ Name ]:
Diphosgene
[Synonym ]:
Diphosgen
perchloromethylformate
Trichloromethyl chloroformate
Trichlormethylchlorformiat
trichloromethyl chloroformiate
di-Phosgene
Disphosgene
Chloroformic acid trichloromethyl ester
MFCD00015553
Difosgen
Perstoff
EINECS 207-965-9
Diphosgene
Trichloromethyl carbonochloridate
trichloro-methanochloroformate
Carbonochloridic acid, trichloromethyl ester
Chemical & Physical Properties
[ Density]:
1.8±0.1 g/cm3
[ Boiling Point ]:
128.0±0.0 °C at 760 mmHg
[ Melting Point ]:
-57 °C
[ Molecular Formula ]:
C2Cl4O2
[ Molecular Weight ]:
197.832
[ Flash Point ]:
32.2±24.9 °C
[ Exact Mass ]:
195.865234
[ PSA ]:
26.30000
[ LogP ]:
2.85
[ Vapour Pressure ]:
10.8±0.2 mmHg at 25°C
[ Index of Refraction ]:
1.499
[ Water Solubility ]:
may decompose
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LQ7350000
- CHEMICAL NAME :
- Formic acid, chloro-, trichloromethyl ester
- CAS REGISTRY NUMBER :
- 503-38-8
- BEILSTEIN REFERENCE NO. :
- 0970225
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C2-Cl4-O2
- MOLECULAR WEIGHT :
- 197.82
- WISWESSER LINE NOTATION :
- GXGGOVG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 900 mg/m3/15M
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - ciliary function changes Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- FMORAO Folia Morphologica (Prague). (Plenum Pub. Corp. 233 Spring St., New York, NY 10013) V.13- 1965- Volume(issue)/page/year: 19,5,1971
Safety Information
[ Symbol ]:
GHS05, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300 + H330-H314
[ Precautionary Statements ]:
P260-P264-P280-P284-P301 + P310-P305 + P351 + P338
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T+:Verytoxic;
[ Risk Phrases ]:
R26/27/28;R34
[ Safety Phrases ]:
S26-S28-S36/37/39-S45-S28A
[ RIDADR ]:
UN 3277 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
LQ7350000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
2915900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2915900090
[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%
Articles
Talanta 80(1) , 231-5, (2009)
Methods for the detection and estimation of diphosgene and triphosgene are described. These compounds are widely used phosgene precursors which produce an intensely colored purple pentamethine oxonol ...
Acute nose-only inhalation exposure of rats to di- and triphosgene relative to phosgene.Inhal. Toxicol. 23(2) , 65-73, (2011)
Groups of young adult Wistar rats were acutely exposed to trichloromethyl chloroformate (diphosgene) and bis(trichloromethyl) carbonate (triphosgene) vapor atmospheres using a directed-flow nose-only ...
Potential agents of chemical warfare. Worst-case scenario protection and decontamination methods.Postgrad. Med. 112(5) , 133-40, (2002)