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Eprobemide

Names

[ CAS No. ]:
87940-60-1

[ Name ]:
Eprobemide

[Synonym ]:
4-chloro-N-[3-(morpholin-4-yl)propyl]benzamide
Eprobemide

Biological Activity

[Description]:

Eprobemide is a non-competitive reversible inhibitor of monoamine oxidase A.

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase
Research Areas >> Neurological Disease

[Target]

Monoamine oxidase A[1][2]


[In Vitro]

Eprobemide is a pharmaceutical drug that is used as an antidepressant. Eprobemide is a non-competitive reversible inhibitor of monoamine oxidase A that exhibits selective action on serotonin deamination[1][2].

[References]

[1]. Gol'dina OA, et al. The action of befol and its derivatives on monoamine oxidase of different origins. Biull Eksp Biol Med. 1991 Mar;111(3):279-80.

[2]. Donskaya, et al. Antidepressant Befol Synthesized Via Interaction of 4-Chloro-N-(3-chloropropyl)benzamide with Morpholine. Pharmaceutical Chemistry Journal, 2004 Jun; 38(7): 381-384.


[Related Small Molecules]

Phenelzine (sulfate) | trans-2-Phenylcyclopropylamine hemisulfate salt | Clorgyline hydrochloride | Rosmarinic acid | pargyline hydrochloride | GSK-LSD1 Dihydrochloride | Rasagiline mesylate | Mofegiline hydrochloride | Paeonol | Iproniazid (phosphate) | Safinamide | TVP1022 | Minaprine | Nialamide | Desmethoxyyangonin

Chemical & Physical Properties

[ Density]:
1.181g/cm3

[ Boiling Point ]:
461.2ºC at 760 mmHg

[ Molecular Formula ]:
C14H19ClN2O2

[ Molecular Weight ]:
282.76600

[ Flash Point ]:
232.7ºC

[ Exact Mass ]:
282.11400

[ PSA ]:
41.57000

[ LogP ]:
2.12090

[ Index of Refraction ]:
1.545

[ Storage condition ]:
2-8℃

Related Compounds

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