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Gsk317354a

Names

[ CAS No. ]:
874119-13-8

[ Name ]:
Gsk317354a

Biological Activity

[Description]:

GSK317354A is a ROCK and GRK inhibitor. GSK317354A can be used for heart failure and Parkinson’s disease research[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Cell Cycle/DNA Damage >> ROCK
Research Areas >> Neurological Disease
Signaling Pathways >> Stem Cell/Wnt >> ROCK
Signaling Pathways >> TGF-beta/Smad >> ROCK

[Target]

ROCK


[References]

[1]. Homan KT, et al. Identification and structure-function analysis of subfamily selective G protein-coupled receptor kinase inhibitors. ACS Chem Biol. 2015 Jan 16;10(1):310-9.  

Chemical & Physical Properties

[ Molecular Formula ]:
C25H18F4N6O

[ Molecular Weight ]:
494.44

Related Compounds