NK-1 Antagonist 1

Names

[ CAS No. ]:
873947-10-5

[ Name ]:
NK-1 Antagonist 1

Biological Activity

[Description]:

NK-1 Antagonist 1 is an antagonist of NK-1 receptor, used in the research of NK-1 related diseases and conditions such as cough, overactive bladder, alcohol dependency and depression.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor
Research Areas >> Neurological Disease

[Target]

NK-1 receptor[1]


[In Vitro]

NK-1 Antagonist 1 is an antagonist of NK-1 receptor, used in the research of NK-1 related diseases and conditions including cough, overactive bladder, alcohol dependency and depression[1].

[References]

[1]. Jane H. Hsiao, et al. Heteroaryl carbonitriles for the treatment of disease. WO2017011445A1.


[Related Small Molecules]

Substance P acetate salt | rolapitant | SB-222200 | Fezolinetant | Netupitant | [Sar9,Met(O2)11]-Substance P TFA | MLE-4901 | Succinyl-(Asp6,N-Me-Phe8)-Substance P (6-11) | Maropitant | NKP608 | Serlopitant | Talnetant | Y1 receptor antagonist 1 | [bAla8]-Neurokinin A(4-10)

Chemical & Physical Properties

[ Molecular Formula ]:
C25H23F6N5O2

[ Molecular Weight ]:
539.47

Related Compounds