potassium t-butoxide

Names

[ CAS No. ]:
865-47-4

[ Name ]:
potassium t-butoxide

[Synonym ]:
potassium,2-methylpropan-2-olate
tBuOK
Kalium-2-methylpropan-2-olat
KOtBu
MFCD00012162
potassium t-butoxide
Potassium tert-butoxide
tert-Butoxide, potassium
potassium 2-methylpropan-2-olate
EINECS 212-740-3
Potassium 2-methyl-2-propanolate
2-Propanol, 2-methyl-, potassium salt (1:1)

Biological Activity

[Description]:

Potassium tert-butoxide (Potassiumtbutoxide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
0.910 g/mL at 20 °C

[ Boiling Point ]:
275°C

[ Melting Point ]:
256-258 °C (dec.)(lit.)

[ Molecular Formula ]:
C₄H₉KO

[ Molecular Weight ]:
112.21

[ Flash Point ]:
54 °F

[ Exact Mass ]:
112.029045

[ PSA ]:
23.06000

[ LogP ]:
1.21540

[ Vapour Pressure ]:
1 mm Hg ( 220 °C)

[ Storage condition ]:
Flammables area

[ Stability ]:
Stable, but reacts violently with water and acids, possibly leading to fire. Incompatible with water, acids, halogenated hydrocarbons, alcohols, strong oxidizing agents, ketones, carbon dioxide.

[ Water Solubility ]:
REACTS

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H228-H260-H314

[ Supplemental HS ]:
Reacts violently with water.

[ Precautionary Statements ]:
P210-P231 + P232-P280-P305 + P351 + P338-P370 + P378-P402 + P404

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R11;R14;R19;R35

[ Safety Phrases ]:
S16-S26-S36/37/39-S43-S45-S7/9-S8-S43A-S33-S27

[ RIDADR ]:
UN 3274 3/PG 2

[ WGK Germany ]:
1

[ Packaging Group ]:
I

[ Hazard Class ]:
8

[ HS Code ]:
29051900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles

Silylation of C-H bonds in aromatic heterocycles by an Earth-abundant metal catalyst.

Nature 518(7537) , 80-4, (2015)

Heteroaromatic compounds containing carbon-silicon (C-Si) bonds are of great interest in the fields of organic electronics and photonics, drug discovery, nuclear medicine and complex molecule synthesi...

Encapsulation of fish oil with N-stearoyl O-butylglyceryl chitosan using membrane and ultrasonic emulsification processes.

Carbohydr. Polym. 123 , 432-42, (2015)

Fish oil-loaded microcapsules were prepared from oil-in-water emulsions using N-stearoyl O-butylglyceryl chitosan as shell material. The emulsions were prepared by both membrane and ultrasonic emulsif...

Utilizing capillary gas chromatography mass spectrometry to determine 4-benzotrifluoride t-butyl ether as a reaction by-product in fluoxetine synthesized using potassium t-butoxide as base.

J. Pharm. Biomed. Anal. 31(1) , 63-74, (2003)

Fluoxetine hydrochloride has been prepared using two similar synthetic routes, both of which rely upon an ether formation reaction mediated by a base. The base used can affect the impurity profile of ...