1-Naphthyl acetate

Names

[ CAS No. ]:
830-81-9

[ Name ]:
1-Naphthyl acetate

[Synonym ]:
1-Naphthalenol, acetate
naphthalen-1-yl acetate
EINECS 212-599-8
MFCD00003922
1-Naphthyl acetate
Naphthalenol, acetate

Biological Activity

[Description]:

1-Naphthyl acetate is an attractive chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity. 1-Naphthyl acetate has the potential to detect organophosphorus pesticide (OP) poisoning[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Neuronal Signaling >> AChE

[Target]

AChE[1]

[References]

[1]. Chowdhary S, et al. 1-Naphthyl acetate: A chromogenic substrate for the detection of erythrocyte acetylcholinesterase activity. Biochimie. 2018 Nov;154:194-209.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
310.0±11.0 °C at 760 mmHg

[ Melting Point ]:
43-46 °C(lit.)

[ Molecular Formula ]:
C₁₂H₁₀O₂

[ Molecular Weight ]:
186.207

[ Flash Point ]:
110.4±8.2 °C

[ Exact Mass ]:
186.068085

[ PSA ]:
26.30000

[ LogP ]:
2.79

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.604

[ Water Solubility ]:
dioxane: 0.1 g/mL, clear, colorless

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QL2975500

CHEMICAL NAME :: 1-Naphthol, acetate

CAS REGISTRY NUMBER :: 830-81-9

BEILSTEIN REFERENCE NO. :: 2046403

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C12-H10-O2

MOLECULAR WEIGHT :: 186.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 10 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 241,109,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3759 No. of Facilities: 32 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 99 (estimated) No. of Female Employees: 96 (estimated)

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R41

[ Safety Phrases ]:
S26-S39-S24/25-S22-S45-S36/37-S16

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
QL2975500

[ HS Code ]:
2915390090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2915390090

[ Summary ]:
2915390090. esters of acetic acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:5.5%. General tariff:30.0%

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Evidence of multiple/cross resistance to Bt and organophosphate insecticides in Puerto Rico population of the fall armyworm, Spodoptera frugiperda.

Pestic. Biochem. Physiol. 122 , 15-21, (2015)

Fall armyworm (FAW) is a damaging pest of many economic crops. Long-term use of chemical control prompted resistance development to many insecticide classes. Many populations were found to be signific...

Related Compounds

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