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a-Toxicarol

Names

[ CAS No. ]:
82-09-7

[ Name ]:
a-Toxicarol

[Synonym ]:
3H-Bis(1)benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one, 13,13a-dihydro-6-hydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aS-cis)-
(7aS,13aS)-6-Hydroxy-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one
3H-[1]Benzopyrano[3,4-b]pyrano[2,3-h][1]benzopyran-7(7aH)-one, 13,13a-dihydro-6-hydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aS,13aS)-
a-Toxicarol
(7aS-cis)-13,13a-Dihydro-6-hydroxy-9,10-dimethoxy-3,3-dimethyl-3H-bis(1)benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one

Biological Activity

[Description]:

α-Toxicarol is a potent inhibitor of EBV.α-Toxicarol significantly inhibits mouse skin tumor in vivo. α-Toxicarol inhibits the TPA-induced EBV-EA activation[1].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Infection

[References]

[1]. Ito, C., et al. Cancer Chemopreventive Activity of Rotenoids fromDerris trifoliata . Planta Medica, 70(6), 585–588.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
607.2±55.0 °C at 760 mmHg

[ Melting Point ]:
222℃

[ Molecular Formula ]:
C23H22O7

[ Molecular Weight ]:
410.42

[ Flash Point ]:
213.0±25.0 °C

[ Exact Mass ]:
410.136566

[ PSA ]:
83.45000

[ LogP ]:
6.06

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.600

Precursor & DownStream

Precursor

DownStream

Related Compounds