A-908292
Names
[ CAS No. ]:
903886-95-3
[ Name ]:
A-908292
Biological Activity
[Description]:
A-908292 is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 38 nM (hACC2), no activity against ACC1 (IC50>30 uM).
[References]
1. Nishiura Y, et al. Bioorg Med Chem Lett. 2018 Aug 1;28(14):2498-2503. 2. Takagi H, et al. J Pharmacol Exp Ther. 2020 Mar;372(3):256-263. 3. Waring JF, et al. J Pharmacol Exp Ther. 2008 Feb;324(2):507-16.
Chemical & Physical Properties
[ Molecular Formula ]:
C18H20N2O4S
[ Molecular Weight ]:
360.428