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Bambuterol

Names

[ CAS No. ]:
81732-65-2

[ Name ]:
Bambuterol

[Synonym ]:
Bambuterol (INN)
Bambuterol
Bambec
Bambuterolum [Latin]
[3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate
Bambuterol [BAN:INN]
Oxeol
Bambuterolum

Biological Activity

[Description]:

Bambuterol is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.IC50 value:Target: beta-adrenoceptor agonistBambuterol is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Natural Products >> Others
Research Areas >> Others

[References]

[1]. Bambuterol, From Wikipedia


[Related Small Molecules]

Isoprenaline hydrochloride | ICI 118,551 (hydrochloride) | Phenylephrine hydrochloride | Yohimbine hydrochloride | Adrenaline | Ivabradine hydrochloride | Prazosin hydrochloride | Clenbuterol hydrochloride | Phentolamine mesilate | guanfacine hydrochloride | pimozide | Sotalol hydrochloride | Carvedilol | Atenolol | Metroprolol succinate

Chemical & Physical Properties

[ Density]:
1.154 g/cm3

[ Boiling Point ]:
500.9ºC at 760 mmHg

[ Molecular Formula ]:
C18H29N3O5

[ Molecular Weight ]:
367.44000

[ Flash Point ]:
256.7ºC

[ Exact Mass ]:
367.21100

[ PSA ]:
91.34000

[ LogP ]:
2.61980

[ Storage condition ]:
2-8℃

[ Water Solubility ]:
H2O: ~33 mg/mL, soluble

Safety Information

[ WGK Germany ]:
3

Related Compounds

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