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Notoginsenoside R2

Names

[ CAS No. ]:
80418-25-3

[ Name ]:
Notoginsenoside R2

[Synonym ]:
β-D-Glucopyranoside, (3β,6α,12β)-3,12,20-trihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-
NOTOGINSENOSIDE R1(SH)
notoginsenoside Rh1
NOTOGINSENOSIDE
Sanchinoside R1
notogisenoside R1
20(S)-NotoginsenosideR2
ginsenoside-Rg2
notoginsenoside-Rg2
notoginsenoside-R1
(3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-β-D-glucopyranoside
notoginsenoside-R2
ginsenoside R2
20(S)-Notoginsenoside R2
Notoginsenoside R2

Biological Activity

[Description]:

Notoginsenoside R2 is a newly isolated notoginsenoside from Panax notoginseng, showed neuroprotective effects against 6-OHDA-induced oxidative stress and apoptosis.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Natural Products >> Terpenoids and Glycosides
Research Areas >> Neurological Disease

[References]

[1]. Meng XB, et al. P90RSK and Nrf2 Activation via MEK1/2-ERK1/2 Pathways Mediated by Notoginsenoside R2 to Prevent 6-Hydroxydopamine-Induced Apoptotic Death in SH-SY5Y Cells. Evid Based Complement Alternat Med. 2013;2013:971712.

[2]. González-Burgos E, et al. Potential neuroprotective activity of Ginseng in Parkinson's disease: a review. J Neuroimmune Pharmacol. 2015 Mar;10(1):14-29.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
878.7±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C41H70O13

[ Molecular Weight ]:
770.987

[ Flash Point ]:
485.2±34.3 °C

[ Exact Mass ]:
770.481628

[ PSA ]:
218.99000

[ LogP ]:
6.45

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.597

[ Storage condition ]:
2-8°C

Related Compounds