Ethyl α-hydroxyisobutyrate

Names

[ CAS No. ]:
80-55-7

[ Name ]:
Ethyl α-hydroxyisobutyrate

[Synonym ]:
Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester (9CI)
Ethyl α-hydroxyisobutyrate
Ethyl 2-hydroxy-2-methylpropanoate
EINECS 201-290-3
Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester
MFCD00004458

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
152.1±8.0 °C at 760 mmHg

[ Molecular Formula ]:
C₆H₁₂O₃

[ Molecular Weight ]:
132.158

[ Flash Point ]:
44.4±0.0 °C

[ Exact Mass ]:
132.078644

[ PSA ]:
46.53000

[ LogP ]:
0.16

[ Vapour Pressure ]:
1.3±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.428

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OD5672000

CHEMICAL NAME :: Lactic acid, 2-methyl-, ethyl ester

CAS REGISTRY NUMBER :: 80-55-7

BEILSTEIN REFERENCE NO. :: 0878308

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H12-O3

MOLECULAR WEIGHT :: 132.18

WISWESSER LINE NOTATION :: QX1&1&VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 76,189,1942 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7053 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 919 (estimated) No. of Female Employees: 306 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R10;R36/38

[ Safety Phrases ]:
S26-S36-S16

[ RIDADR ]:
UN 3272 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
OD5672000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
29181980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%