Diethyloxalate
Names
[ CAS No. ]:
95-92-1
[ Name ]:
Diethyloxalate
[Synonym ]:
diethyl ester of oxalic acid
diethyl ethane-1,2-dioate
oxalic diethyl ester
DIETHYL OXALATE FOR PHARMA SYNTHESIS
Oxalic ether
diethyl dicarboxylate
DI ETHYL OXALATE
Ethanedioic acid,diethyl ester
EINECS 202-464-1
ETHYL OXALATE
MFCD00009119
OXALIC ACID DIETHYL ESTER
DIETHYL OXALATE (2.5 LT PVC)
Diethyloxalate
diethyl ethanedioate
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
185.4±0.0 °C at 760 mmHg
[ Melting Point ]:
−41 °C(lit.)
[ Molecular Formula ]:
C6H10O4
[ Molecular Weight ]:
146.141
[ Flash Point ]:
75.6±0.0 °C
[ Exact Mass ]:
146.057907
[ PSA ]:
52.60000
[ LogP ]:
0.73
[ Vapour density ]:
5.03 (vs air)
[ Vapour Pressure ]:
0.7±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.411
[ Stability ]:
Stable, but moisture sensitive. Incompatible with strong oxidizing agents.
[ Water Solubility ]:
MAY DECOMPOSE
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RO2800000
- CHEMICAL NAME :
- Oxalic acid, diethyl ester
- CAS REGISTRY NUMBER :
- 95-92-1
- BEILSTEIN REFERENCE NO. :
- 0606350
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C6-H10-O4
- MOLECULAR WEIGHT :
- 146.16
- WISWESSER LINE NOTATION :
- 2OVVO2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,373,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 46(5),87,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5432 No. of Facilities: 96 (estimated) No. of Industries: 2 No. of Occupations: 17 No. of Employees: 1483 (estimated)
Safety Information
[ Symbol ]:
GHS05, GHS07, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H314-H360FD-H371-H372
[ Precautionary Statements ]:
P201-P260-P280-P305 + P351 + P338-P308 + P311-P310
[ Target Organs ]:
Kidney
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36
[ Safety Phrases ]:
S23
[ RIDADR ]:
UN 2525 6.1/PG 3
[ WGK Germany ]:
1
[ RTECS ]:
RO2800000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2917119000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2917119000
[ Summary ]:
2917119000 oxalic acid salts and esters VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
J. Photochem. Photobiol. B, Biol. 142 , 8-19, (2015)
A condensation reaction between 1,2-diphenylethane-1,2-dione dihydrazone (DPEDDH) and dimethyl or diethyloxalate in methanol resulted in a novel Schiff base octaazamacrocyclic ligand, (L): (6,7,14,15-...
Cerium nitrate: a new topical antiseptic for extensive burns.Surgery 80(4) , 465-73, (1976)
The wounds of 60 burned patients were treated topically with cerium nitrate, which was applied either as a cream or in aqueous solution. Cerium nitrate has a potent antiseptic effect in human burn wou...
Diethyl oxalate as new reagent for spectrophotometric determination of ketosteroids.Anal. Chem. 42(6) , 560-3, (1970)