Ethyl acetopyruvate
Names
[ CAS No. ]:
615-79-2
[ Name ]:
Ethyl acetopyruvate
[Synonym ]:
Ethyl acetopyruvate
EINECS 210-447-5
Ethyl 2,4-dioxovalerate
Ethyl 2,4-dioxopentanoate
Pentanoic acid, 2,4-dioxo-, ethyl ester
MFCD00009124
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
214.7±13.0 °C at 760 mmHg
[ Melting Point ]:
16-18 °C(lit.)
[ Molecular Formula ]:
C7H10O4
[ Molecular Weight ]:
158.152
[ Flash Point ]:
85.8±19.9 °C
[ Exact Mass ]:
158.057907
[ PSA ]:
60.44000
[ LogP ]:
-0.19
[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.426
[ Storage condition ]:
2-8°C
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
S23-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
29183000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2918300090
[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Tetrahedron Asymmetry 9(16) , 2765-2768, (1998)
Preparation of 1-(4-methoxyphenyl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones as potent, selective and bioavailable inhibitors of coagulation factor Xa.
Bioorg. Med. Chem. Lett. 16 , 3755, (2006)
Previously, potent factor Xa inhibitors were described based on a pyrazole core. Modifications of the pyrazole core have provided additional novel, highly potent factor Xa inhibitors. This manuscript ...
Identification of novel pyrazole acid antagonists for the EP1 receptor.Bioorg. Med. Chem. Lett. 16 , 4767, (2006)
The discovery, synthesis and structure-activity relationship (SAR) of a novel series of EP1 receptor antagonists is described. Pyrazole acid 4, identified from a chemical array, had desirable physicoc...