(±)-Amiflamine

Names

[ Name ]:
(±)-Amiflamine

[Synonym ]:
amiflamine
[4-(2-Amino-propyl)-3-methyl-phenyl]-dimethyl-amine
(+/-)-4-dimethylamino-α,2-dimethylphenethylamine

Biological Activity

[Description]:

(±)-Amiflamine (FLA 336) is a potent monoamine oxidase-A (MAO-A) inhibitor with a pIC50 of 5.57[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase

Research Areas >> Neurological Disease

[Target]

MAO-A:5.57 (pIC50)

[References]

[1]. Vallejos G, et al. Charge-transfer interactions in the inhibition of MAO-A by phenylisopropylamines--a QSAR study. J Comput Aided Mol Des. 2002;16(2):95-103.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₂₀N₂

[ Molecular Weight ]:
192.30100

[ Exact Mass ]:
192.16300

[ PSA ]:
29.26000

[ LogP ]:
2.65100

Related Compounds

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