m-PEG3-Amine

Names

[ CAS No. ]:
74654-07-2

[ Name ]:
m-PEG3-Amine

[Synonym ]:
2-[2-(2-methoxyethoxy)ethoxy]ethanamine
2-[2-(2-methoxyethoxy)ethoxy]ethylamine

Biological Activity

[Description]:

m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Nianhe Han, et al. The derivant of aplysiatoxin 10 and application thereof. CN106279352A.

Chemical & Physical Properties

[ Density]:
0.978g/cm3

[ Boiling Point ]:
223.9ºC at 760 mmHg

[ Molecular Formula ]:
C₇H₁₇NO₃

[ Molecular Weight ]:
163.21500

[ Flash Point ]:
86.1ºC

[ Exact Mass ]:
163.12100

[ PSA ]:
53.71000

[ LogP ]:
0.32500

[ Index of Refraction ]:
1.431

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

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