m-PEG3-Tos

Names

[ Name ]:
m-PEG3-Tos

[Synonym ]:
3,6,9-trioxadecyl tosylate
2-[2-(2-Methoxyethoxy)ethoxy]ethanol - 4-methylbenzenesulfonic acid (1:1)
CH3(OCH2CH2)3OTs
Ethanol, 2-[2-(2-methoxyethoxy)ethoxy]-, compd. with 4-methylbenzenesulfonic acid (1:1)
Ethanol,2-[2-(2-methoxyethoxy)ethoxy]-,4-methylbenzenesulfonate
CH3OC2H4OC2H4OC2H4OTs
2-[2-(2-Methoxyethoxy)ethoxy]ethyl 4-methylbenzenesulfonate
triethyleneglycol monotosylate
triethylene glycol methyl tosyl ether
triethyleneglycol monomethyl ether tosylate

Biological Activity

[Description]:

m-PEG3-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[References]

[1]. Yuxia Zhao, et al. Derivative of silybin ethers, and synthetic method and application thereof. Patent CN105037337A.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₂₂O₆S

[ Molecular Weight ]:
336.401

[ Flash Point ]:
215 °C

[ Exact Mass ]:
336.124268

[ PSA ]:
110.67000

[ LogP ]:
1.98080

[ Index of Refraction ]:
1.53

Related Compounds

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