FMOC-ASP(OTBU)-OH

Names

[ CAS No. ]:
71989-14-5

[ Name ]:
FMOC-ASP(OTBU)-OH

[Synonym ]:
L-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) ester
FMOC-L-Asparticacidbeta-tert-butylester
4-tert-Butyl hydrogen N-((9H-fluoren-9-ylmethoxy)carbonyl)-L-aspartate
(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-[(2-methyl-2-propanyl)oxy]-4-oxobutanoic acid
MFCD00037131
FMOC-L-Aspartic acid beta-tert-butyl ester
N-α-FMOC-L-aspartic acid β-tert-butyl ester
Fmoc-L-aspartic acid 4-tert-butyl ester
Fmoc-Asp(OtBu)-OH
EINECS 276-251-7
(2S)-4-tert-Butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxobutanoic acid (non-preferred name)
9-fluorenyl-methoxycarbonyl-L-Asp-tert-butyl ester

Biological Activity

[Description]:

Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Esquivel J B, et al. Chiral HPLC separation of protected amino acids. Journal of liquid chromatography & related technologies, 1998, 21(6): 777-791.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
620.8±55.0 °C at 760 mmHg

[ Melting Point ]:
148-150 °C (dec.)

[ Molecular Formula ]:
C₂₃H₂₅NO₆

[ Molecular Weight ]:
411.448

[ Flash Point ]:
329.3±31.5 °C

[ Exact Mass ]:
411.168182

[ PSA ]:
101.93000

[ LogP ]:
5.16

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.576

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Evaluation of a nonpeptidic ligand for imaging of cholecystokinin 2 receptor-expressing cancers.

J. Nucl. Med. 56(1) , 113-9, (2015)

Tumor-specific targeting ligands were recently exploited to deliver both imaging and therapeutic agents selectively to cancer tissues in vivo. Because the cholecystokinin 2 receptor (CCK2R) is overexp...

Correlations of amyloid-β concentrations between CSF and plasma in acute Alzheimer mouse model.

Sci. Rep. 4 , 6777, (2014)

Amyloid-β (Aβ) is one of the few neuropathological biomarkers associated with transporters of the blood-brain barrier (BBB). Despite the well-characterized clinical indication of decreasing Aβ levels ...

Related Compounds

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