α-Conotoxin PnIA TFA

Names

[ Name ]:
α-Conotoxin PnIA TFA

[Synonym ]:
a-conotoxin pnia

Biological Activity

[Description]:

α-Conotoxin PnIA, a potent and selective antagonist of the mammalian α7 nAChR, has the potential for the research of neurological conditions such as neuropathic pain and Alzheimer’s disease[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR

Signaling Pathways >> Neuronal Signaling >> nAChR

Research Areas >> Neurological Disease

[References]

[1]. Gene Hopping, et al. Hydrophobic Residues at Position 10 of α-conotoxin PnIA Influence Subtype Selectivity Between α7 and α3β2 Neuronal Nicotinic Acetylcholine Receptors. Biochem Pharmacol. 2014 Oct 15;91(4):534-42.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₅H₉₅N₁₉O₂₂S₄

[ Molecular Weight ]:
1622.82000

[ Exact Mass ]:
1621.58000

[ PSA ]:
744.38000

Related Compounds

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