DL-Lysine

Names

[ CAS No. ]:
70-54-2

[ Name ]:
DL-Lysine

[Synonym ]:
Lysine, DL-
MFCD00064432
(±)-Lysine
Lys
H-DL-Lys-OH
EINECS 200-740-6
[1R-(2-endo,3-exo)]-8-Methyl-3-phenyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester
(±)-2,6-Diaminohexanoic Acid
DL-Lysine
LYSINE (DL)
DL-α,ε-Diaminocaproic Acid
Benzonitrile,2,6-diamino
Lysine
H-Lys-OH

Biological Activity

[Description]:

DL-Lysine (Lysine) is an α-amino acid that is used in the biosynthesis of proteins.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Others

[Target]

Km: 100-400 μM (amino acid transporter b0,+)[1]

[In Vitro]

DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].

[References]

[1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
311.5±32.0 °C at 760 mmHg

[ Melting Point ]:
170ºC (dec.)

[ Molecular Formula ]:
C₆H₁₄N₂O₂

[ Molecular Weight ]:
146.188

[ Flash Point ]:
142.2±25.1 °C

[ Exact Mass ]:
146.105530

[ PSA ]:
89.34000

[ LogP ]:
-1.04

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.503

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
T+:Very toxic

[ Safety Phrases ]:
S1-S28-S45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922411000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922411000

[ Summary ]:
HS: 2922411000. 2,6-diaminohexanoic acid. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:ab(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tarrif:5.0%. general tariff:20.0%

Articles

The protein phosphatase Siw14 controls caffeine-induced nuclear localization and phosphorylation of Gln3 via the type 2A protein phosphatases Pph21 and Pph22 in Saccharomyces cerevisiae.

J. Biochem. 157(1) , 53-64, (2015)

The Saccharomyces cerevisiae Siw14, a tyrosine phosphatase involved in the response to caffeine, participates in regulation of the phosphorylation and intracellular localization of Gln3, a GATA transc...

Functional study of the Hap4-like genes suggests that the key regulators of carbon metabolism HAP4 and oxidative stress response YAP1 in yeast diverged from a common ancestor.

PLoS ONE 9(12) , e112263, (2014)

The transcriptional regulator HAP4, induced by respiratory substrates, is involved in the balance between fermentation and respiration in S. cerevisiae. We identified putative orthologues of the Hap4 ...

The tyrosine phosphatase PTPN14 (Pez) inhibits metastasis by altering protein trafficking.

Sci. Signal. 8(364) , ra18, (2015)

Factors secreted by tumor cells shape the local microenvironment to promote invasion and metastasis, as well as condition the premetastatic niche to enable secondary-site colonization and growth. In a...