D-Lysine

Names

[ CAS No. ]:
923-27-3

[ Name ]:
D-Lysine

[Synonym ]:
(R)-2,6-Diaminocaproic acid
(R)-lysine
EINECS 213-091-9
Benzonitrile,2,6-diamino
D-Lysine
Lysine
D-2,6-Diaminohexanoic acid
(2R)-2,6-diaminohexanoic acid
(R)-2,6-Diaminohexanoic acid
r-lysine
MFCD00008234

Biological Activity

[Description]:

D-Lysine is a useful raw material employed as an analog of lutenizing-hormone-releasing hormone and as a drug carrier in the form of polylysine. D-Lysine decreases renal uptake of radioactivity during scintigraphy and PRRT with low toxicity. D-Lysine not interferes with the natural amino acid metabolic balance[1][2].

[Related Catalog]:

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[In Vivo]

D-Lysine (400 mg/kg; i.v. or p.o.) dose not result in significantly greater inhibition of kidney uptake of '"In-DTPAOC, and Oral administration of D-lysine also reduces kidney uptake in rats[1].

[References]

[1]. Bernard BF, et al. D-lysine reduction of indium-111 octreotide and yttrium-90 octreotide renal uptake. J Nucl Med. 1997 Dec;38(12):1929-33.

[2]. Takahashi E, et al. D-lysine production from L-lysine by successive chemical racemization and microbial asymmetric degradation. Appl Microbiol Biotechnol. 1997 Apr;47(4):347-51.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
311.5±32.0 °C at 760 mmHg

[ Melting Point ]:
218ºC (dec.)

[ Molecular Formula ]:
C₆H₁₄N₂O₂

[ Molecular Weight ]:
146.188

[ Flash Point ]:
142.2±25.1 °C

[ Exact Mass ]:
146.105530

[ PSA ]:
89.34000

[ LogP ]:
-1.04

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.503

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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