N-Boc-L-Prolinol

Names

[ Name ]:
N-Boc-L-Prolinol

[Synonym ]:
tert-butyl (2S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
tert-butyl (S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
(S)-(-)-1-Boc-2-pyrrolidinemethanol
MFCD00066232
N-Boc-L-prolinol
2-Methyl-2-propanyl (2S)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate
Boc-Pro-Ol

Biological Activity

[Description]:

1-Boc-2-(S)-pyrrolidinemethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
289.5±13.0 °C at 760 mmHg

[ Melting Point ]:
60-64ºC

[ Molecular Formula ]:
C₁₀H₁₉NO₃

[ Molecular Weight ]:
201.26

[ Flash Point ]:
128.9±19.8 °C

[ Exact Mass ]:
201.136490

[ PSA ]:
49.77000

[ LogP ]:
0.46

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.484

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Design, synthesis and biological activity of amidinobicyclic compounds (derivatives of DX-9065a) as factor Xa inhibitors: SAR study of S1 and aryl binding sites.

Bioorg. Med. Chem. 12 , 2099-2114, (2004)

Since factor Xa (fXa) plays a pivotal role in the blood coagulation cascade, inhibition of fXa is thought to be an effective treatment for a variety of thrombotic events. (2S)-2-[4-[[(3S)-1-Acetimidoy...

Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors.

J. Med. Chem. 39 , 817-825, (1996)

Recent evidence indicating the therapeutic potential of cholinergic channel modulators for the treatment of central nervous system (CNS) disorders as well as the diversity of brain neuronal nicotine a...

Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties.

J. Med. Chem. 40 , 385, (1997)

2-Methyl-3-(2(S)-pyrrolidinylmethoxy)pyridine, ABT-089 (S-4), a member of the 3-pyridyl ether class of nicotinic acetylcholine receptor (nAChR) ligands, shows positive effects in rodent and primate mo...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.