Xanthoplanine

Names

[ Name ]:
Xanthoplanine

Biological Activity

[Description]:

Xanthoplanine, isolated from theroot of Xylopia parviflora, fully inhibits the EC50 ACh responses of both alpha7 and alpha4beta2 nACh receptors with estimated IC50 values of 9 μM (alpha7) and 5 μM (alpha4beta2)[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR

Signaling Pathways >> Neuronal Signaling >> nAChR

Research Areas >> Neurological Disease

[References]

[1]. Iturriaga-Vásquez P, et al. Aporphine metho salts as neuronal nicotinic acetylcholine receptor blockers.Bioorg Med Chem. 2007 May 15;15(10):3368-72.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₆NO₄

[ Molecular Weight ]:
356.43500

[ Exact Mass ]:
356.18600

[ PSA ]:
47.92000

[ LogP ]:
3.27350

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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