N-acetyl-L-proline
Names
[ CAS No. ]:
68-95-1
[ Name ]:
N-acetyl-L-proline
[Synonym ]:
N-Acetyl-L-proline
EINECS 200-698-9
Proline, 1-acetyl-, L-
MFCD00020837
(2S)-1-acetylpyrrolidine-2-carboxylic acid
L-Proline, 1-acetyl-
1-Acetyl-L-proline
N-Acethyl-L-proline
Ac-Pro-OH
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
366.2±35.0 °C at 760 mmHg
[ Melting Point ]:
115-117 °C
[ Molecular Formula ]:
C7H11NO3
[ Molecular Weight ]:
157.17
[ Flash Point ]:
175.3±25.9 °C
[ Exact Mass ]:
157.073898
[ PSA ]:
57.61000
[ LogP ]:
-0.77
[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C
[ Index of Refraction ]:
1.517
[ Storage condition ]:
2~8°C
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi: Irritant;
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ Packaging Group ]:
I; II; III
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Phys. Chem. A 113(40) , 10858-65, (2009)
Nuclear magnetic resonance (NMR) and quantum mechanical (QM) studies have been carried out for proline (Pro) containing peptides: N-acetyl-l-proline (AcProOH) and N-acetyl-4-hydroxy-l-proline (AcHypOH...
Angiotensin-converting enzyme inhibitors. Mercaptan, carboxyalkyl dipeptide, and phosphinic acid inhibitors incorporating 4-substituted prolines.J. Med. Chem. 31 , 1148-1160, (1988)
Analogues of captopril, enalaprilat, and the phosphinic acid [hydroxy(4-phenylbutyl)phosphinyl]acetyl]-L-proline incorporating 4-substituted proline derivatives have been synthesized and evaluated as ...
Synergistic binding of ligands to angiotensin-converting enzyme.J. Biol. Chem. 263 , 4056-4068, (1988)
We have investigated the interaction of ligands in the active site of the angiotensin-converting enzyme from rabbit lung by monitoring the concurrent effects of two inhibitors on enzyme activity. A st...