4-PHENYLIMIDAZOLE

[Description]:

[Related Catalog]:

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
379.8±11.0 °C at 760 mmHg

[ Melting Point ]:
128-131 °C(lit.)

[ Molecular Formula ]:
C₉H₈N₂

[ Molecular Weight ]:
144.17

[ Flash Point ]:
213.0±5.7 °C

[ Exact Mass ]:
144.068741

[ PSA ]:
28.68000

[ LogP ]:
1.46

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.603

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933290090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Novel synthetic pyridyl analogues of CDDO-Imidazolide are useful new tools in cancer prevention.

Pharmacol. Res. 100 , 135-47, (2015)

Two new analogues of CDDO-Imidazolide (CDDO-Im), namely 1-[2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]-4(-pyridin-2-yl)-1H-imidazole ("CDDO-2P-Im") and 1-[2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oy...

Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography.

Antimicrob. Agents Chemother. 51 , 3915-23, (2007)

Sterol 14alpha-demethylase (CYP51), a major checkpoint in membrane sterol biosynthesis, is a key target for fungal antibiotic therapy. We sought small organic molecules for lead candidate CYP51 inhibi...

Calmodulin-dependent nitric-oxide synthase. Mechanism of inhibition by imidazole and phenylimidazoles.

J. Biol. Chem. 268(13) , 9425-9, (1993)

Calmodulin-dependent nitric-oxide synthase from bovine brain and GH3 pituitary cells is inhibited by imidazole, 1-phenylimidazole, 2-phenylimidazole, and 4-phenylimidazole, with half-maximal inhibitio...

More Articles