Rubusoside

Names

[ Name ]:
Rubusoside

[Synonym ]:
Rubusoside
UNII-TCV5K3M3GX
1-O-[(5β,8α,9β,10α,13α)-13-(β-D-Glucopyranosyloxy)-18-oxokaur-16-en-18-yl]-β-D-glucopyranose
1-O-[(5β,8α,9β,10α,13α)-13-(β-D-Glucopyranosyloxy)-19-oxokaur-16-en-19-yl]-β-D-glucopyranose
rubescensin a(rg)

Biological Activity

[Description]:

Rubusoside is a natural sweetener and a solubilizing agent with antiangiogenic and antiallergic properties. Rubusoside is an excellent solubilizing agent. It can enhance the solubility of a number of pharmaceutically important compounds, such as liquiritin, teniposide, curcumin, and etoposide.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Others

Natural Products >> Terpenoids and Glycosides

[References]

[1]. Wang Z et al. Selective production of rubusoside from stevioside by using the sophorose activity of β-glucosidase from Streptomyces sp. GXT6. Appl Microbiol Biotechnol. 2015 Nov;99(22):9663-74.

[2]. Ko JA et al. Mass production of rubusoside using a novel stevioside-specific β-glucosidase from Aspergillus aculeatus. J Agric Food Chem. 2012 Jun 20;60(24):6210-6.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
802.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₂H₅₀O₁₃

[ Molecular Weight ]:
642.732

[ Flash Point ]:
251.9±27.8 °C

[ Exact Mass ]:
642.325134

[ PSA ]:
215.83000

[ LogP ]:
1.83

[ Vapour Pressure ]:
0.0±6.4 mmHg at 25°C

[ Index of Refraction ]:
1.628

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
29389090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Cytotoxic and antiangiogenic paclitaxel solubilized and permeation-enhanced by natural product nanoparticles.

Anticancer Drugs 26(2) , 167-79, (2014)

Paclitaxel (PTX) is one of the most potent intravenous chemotherapeutic agents to date, yet an oral formulation has been problematic because of its low solubility and permeability. Using the recently ...

[Identification and biotransformation properties of a bacterium that converts stevioside into rubusoside].

Wei Sheng Wu Xue Bao 51(1) , 43-9, (2011)

The purpose of our study was to separate and identify a bacillus that could convert stevioside specifically. Then we identified the conversion product and studied the conversion capability of the baci...

[Study on quality control of Rubus suavissimus].

Zhong Yao Cai 31(11) , 1734-7, (2008)

To control the quality of Rubus suavissimus.We inspected the character observation, microscopic, physical and chemical identification, TLC, the examination of water and extraction of Rubus suavissimus...