3-Bromopropan-1-ol

Names

[ CAS No. ]:
627-18-9

[ Name ]:
3-Bromopropan-1-ol

[Synonym ]:
2-Propanone,1-bromo-3-hydroxy
3-bromopropanol-1
3-Bromo-1-propanol
1-bromo-3-hydroxypropanone
3-bromopropan-1-ol
3-bromo-1-hydroxy-2-propanone
1-bromo-3-hydroxy-propan-2-one
EINECS 210-986-6
propylene bromohydrin
1-Propanol, 3-bromo-
3-Brompropan-1-ol
3-bromo-1-hydroxypropan-2-one
1-bromo-3-propanol
MFCD00002942
3-hydroxypropyl bromide
1-bromo-3-hydroxypropane

Biological Activity

[Description]:

3-Bromopropan-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
175.3±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃H₇BrO

[ Molecular Weight ]:
138.99

[ Flash Point ]:
93.9±0.0 °C

[ Exact Mass ]:
137.968018

[ PSA ]:
20.23000

[ LogP ]:
0.34

[ Vapour Pressure ]:
0.4±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.480

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
167 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UA7385000

CHEMICAL NAME :: 1-Propanol, 3-bromo-

CAS REGISTRY NUMBER :: 627-18-9

BEILSTEIN REFERENCE NO. :: 0969160

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C3-H7-Br-O

MOLECULAR WEIGHT :: 139.01

WISWESSER LINE NOTATION :: Q3E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 177 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 57,381,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6644 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S39-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UA7385000

[ HS Code ]:
2905590090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2905590090

[ Summary ]:
2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.

Bioorg. Med. Chem. 16 , 5720-32, (2008)

The risk of the presence of haloacetic acids in drinking water as chlorination by-products and the shortage of experimental mutagenicity data for most of them requires a research work. This paper desc...

Chloride-sensitive fluorescent indicators.

Anal. Biochem. 293(1) , 60-6, (2001)

Three fluorescent halide-sensitive quinolinium dyes have been produced by the reaction of the 6-methylquinoline heterocyclic nitrogen base with methyl bromide, methyl iodide, and 3-bromo-1-propanol. T...

Stereochemical diversity in asymmetric cyclization via memory of chirality.

J. Am. Chem. Soc. 128 , 15394, (2006)

An enantiodivergent asymmetric cyclization of N-Boc-N-omega-bromoalkyl-alpha-amino acid derivatives has been developed. With potassium amide bases in DMF, cyclization proceeds with retention of config...