OMDM-6

Names

[ CAS No. ]:
616884-67-4

[ Name ]:
OMDM-6

Biological Activity

[Description]:

OMDM-6 is a hybrid agonist of vanilloid receptor type 1 (VR1, TRPV1) (EC50=75 nM) and cannabinoid receptor type 1 (CB1) (Ki=3.2 μM). OMDM-6 inhibits anandamide cellular uptake (ACU) with a Ki of 7.0 μM[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel
Research Areas >> Neurological Disease
Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor

[Target]

EC50: 75 nM (vanilloid receptor type 1), Ki: 3.2 μM (cannabinoid receptor type 1), Ki: 7.0 μM (anandamide cellular uptake)[1]


[References]

[1]. Ortar G, et al. Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem Pharmacol. 2003 May 1;65(9):1473-81.

Chemical & Physical Properties

[ Molecular Formula ]:
C28H42N2O3

[ Molecular Weight ]:
454.64

Related Compounds