616884-67-4

616884-67-4 structure

616884-67-4 structure

Name: OMDM-6
Chemical Name: OMDM-6
CAS Number: 616884-67-4
Molecular Formula: C₂₈H₄₂N₂O₃
Molecular Weight: 454.64
Catalog: Signaling Pathways GPCR/G Protein Cannabinoid Receptor
Create Date: 2020-06-01 13:51:11
Modify Date: 2024-01-11 10:39:05
OMDM-6 is a hybrid agonist of vanilloid receptor type 1 (VR1, TRPV1) (EC50=75 nM) and cannabinoid receptor type 1 (CB1) (Ki=3.2 μM). OMDM-6 inhibits anandamide cellular uptake (ACU) with a Ki of 7.0 μM[1].

Name	OMDM-6

Description	OMDM-6 is a hybrid agonist of vanilloid receptor type 1 (VR1, TRPV1) (EC50=75 nM) and cannabinoid receptor type 1 (CB1) (Ki=3.2 μM). OMDM-6 inhibits anandamide cellular uptake (ACU) with a Ki of 7.0 μM[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
Target	EC50: 75 nM (vanilloid receptor type 1), Ki: 3.2 μM (cannabinoid receptor type 1), Ki: 7.0 μM (anandamide cellular uptake)[1]
References	[1]. Ortar G, et al. Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem Pharmacol. 2003 May 1;65(9):1473-81.

Molecular Formula	C₂₈H₄₂N₂O₃
Molecular Weight	454.64