O-Desmethyl galanthamine

Names

[ Name ]:
O-Desmethyl galanthamine

[Synonym ]:
O-Desmethylgalantamine
UNII-L7ZOW3CZ7W
6-demethylgalanthamine
O-Desmethyl Galanthamine
O-Demethylgalanthamine
O-Demethylgalantamine

Biological Activity

[Description]:

O-Desmethyl Galanthamine (Sanguinine) is galanthamine-type alkaloid. O-Desmethyl Galanthamine is an acetylcholinesterase (AChE) inhibitor, with an IC50 1.83 μM[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> AChE

[Target]

AChE[1]

[References]

[1]. Seydou Ka, et al. Gigantelline, gigantellinine and gigancrinine, cherylline- and crinine-type alkaloids isolated from Crinum jagus with anti-acetylcholinesterase activity. Phytochemistry. 2020 Jul;175:112390.

Chemical & Physical Properties

[ Density]:
1.37g/cm3

[ Boiling Point ]:
451.9ºC at 760 mmHg

[ Melting Point ]:
227-230ºC (dec.)

[ Molecular Formula ]:
C₁₆H₁₉NO₃

[ Molecular Weight ]:
273.32700

[ Flash Point ]:
227.1ºC

[ Exact Mass ]:
273.13600

[ PSA ]:
52.93000

[ LogP ]:
1.48520

[ Index of Refraction ]:
1.683

Precursor & DownStream

Precursor

DownStream

Related Compounds

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