NSC 146109 (hydrochloride)
Names
[ CAS No. ]:
59474-01-0
[ Name ]:
NSC 146109 (hydrochloride)
[Synonym ]:
10-Methyl-9-anthrylmethylisothioharnstoff Hydrochlorid
Biological Activity
[Description]:
NSC 146109 hydrochloride is a small-molecule p53 activator that target MDMX and could be of value in treating breast cancer.NSC 146109 hydrochloride is a pseudourea derivative, promotes breast cancer cells to undergo apoptosis through activating p53 and inducing expression of proapoptotic genes[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.23g/cm3
[ Boiling Point ]:
493.6ºC at 760 mmHg
[ Molecular Formula ]:
C17H17ClN2S
[ Molecular Weight ]:
316.84800
[ Flash Point ]:
252.3ºC
[ Exact Mass ]:
316.08000
[ PSA ]:
61.18000
[ LogP ]:
5.98580
[ Index of Refraction ]:
1.665