59474-01-0
59474-01-0 structure
- Name: NSC 146109 (hydrochloride)
- Chemical Name: (10-methylanthracen-9-yl)methyl carbamimidothioate
- CAS Number: 59474-01-0
- Molecular Formula: C17H17ClN2S
- Molecular Weight: 316.84800
- Catalog: Signaling Pathways Apoptosis MDM-2/p53
- Create Date: 2017-09-07 01:39:46
- Modify Date: 2025-08-26 19:04:10
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NSC 146109 hydrochloride is a small-molecule p53 activator that target MDMX and could be of value in treating breast cancer.NSC 146109 hydrochloride is a pseudourea derivative, promotes breast cancer cells to undergo apoptosis through activating p53 and inducing expression of proapoptotic genes[1].
| Name | (10-methylanthracen-9-yl)methyl carbamimidothioate |
|---|---|
| Synonyms | 10-Methyl-9-anthrylmethylisothioharnstoff Hydrochlorid |
| Description | NSC 146109 hydrochloride is a small-molecule p53 activator that target MDMX and could be of value in treating breast cancer.NSC 146109 hydrochloride is a pseudourea derivative, promotes breast cancer cells to undergo apoptosis through activating p53 and inducing expression of proapoptotic genes[1]. |
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| Related Catalog | |
| References |
| Density | 1.23g/cm3 |
|---|---|
| Boiling Point | 493.6ºC at 760 mmHg |
| Molecular Formula | C17H17ClN2S |
| Molecular Weight | 316.84800 |
| Flash Point | 252.3ºC |
| Exact Mass | 316.08000 |
| PSA | 61.18000 |
| LogP | 5.98580 |
| Index of Refraction | 1.665 |