Hibifolin

Names

[ Name ]:
Hibifolin

[Synonym ]:
Hibifolin

Biological Activity

[Description]:

Hibifolin, a flavonol glycoside, is a potential inhibitor of adenosine deaminase (ADA), with a Ki of 49.92 μM. Hibifolin protects neurons against beta-amyloid-induced neurotoxicity[1][2].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Adenosine Deaminase

[Target]

Ki: 49.92 μM (ADA)[1]

[References]

[1]. K G Arun, et al. Inhibitory activity of hibifolin on adenosine deaminase- experimental and molecular modeling study. Comput Biol Chem. 2016 Oct;64:353-358.

[2]. Judy T T Zhu, et al. Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons. Neurosci Lett. 2009 Sep 18;461(2):172-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₁₈O₁₄

[ Molecular Weight ]:
494.35900

[ Exact Mass ]:
494.07000

[ PSA ]:
247.81000

[ Storage condition ]:
2-8℃

Related Compounds

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