55366-56-8

55366-56-8 structure

Name: Hibifolin
Chemical Name: (2S,3S,4S,5R,6S)-6-[2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4-oxochromen-8-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
CAS Number: 55366-56-8
Molecular Formula: C₂₁H₁₈O₁₄
Molecular Weight: 494.35900
Catalog: Signaling Pathways Metabolic Enzyme/Protease Adenosine Deaminase
Create Date: 2018-11-23 20:42:09
Modify Date: 2025-08-25 19:06:14
Hibifolin, a flavonol glycoside, is a potential inhibitor of adenosine deaminase (ADA), with a Ki of 49.92 μM. Hibifolin protects neurons against beta-amyloid-induced neurotoxicity[1][2].

Name	(2S,3S,4S,5R,6S)-6-[2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4-oxochromen-8-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
Synonyms	Hibifolin

Description	Hibifolin, a flavonol glycoside, is a potential inhibitor of adenosine deaminase (ADA), with a Ki of 49.92 μM. Hibifolin protects neurons against beta-amyloid-induced neurotoxicity[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Adenosine Deaminase
Target	Ki: 49.92 μM (ADA)[1]
References	[1]. K G Arun, et al. Inhibitory activity of hibifolin on adenosine deaminase- experimental and molecular modeling study. Comput Biol Chem. 2016 Oct;64:353-358. [2]. Judy T T Zhu, et al. Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons. Neurosci Lett. 2009 Sep 18;461(2):172-6.