Benzphetamine Hydrochloride
Names
[ CAS No. ]:
5411-22-3
[ Name ]:
Benzphetamine Hydrochloride
[Synonym ]:
Benzphetamine hydrchloride
Benzphetaminhydrochlorid
didrex
Benzyl-methyl-((S)-1-methyl-2-phenyl-aethyl)-amin,Hydrochlorid
(+)-Benzphetamine hydrochloride
(2S)-N-benzyl-N-methyl-1-phenylpropan-2-amine hydrochloride
benzyl-methyl-((S)-1-methyl-2-phenyl-ethyl)-amine,hydrochloride
d-benzphetaminehydrochloride
Benzphetamine Hydrochloride CIII (200 mg)
BENZPHETAMINE HYDROCHLORIDE--DEA
inapetyl
(S)-BenzphetaMine Hydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
334.3ºC at 760mmHg
[ Melting Point ]:
129-130°
[ Molecular Formula ]:
C17H22ClN
[ Molecular Weight ]:
275.81600
[ Flash Point ]:
141.5ºC
[ Exact Mass ]:
275.14400
[ PSA ]:
3.24000
[ LogP ]:
4.55160
[ Storage condition ]:
2-8°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SG9625000
- CHEMICAL NAME :
- Phenethylamine, N-benzyl-N,alpha-dimethyl-, hydrochloride, (+)-
- CAS REGISTRY NUMBER :
- 5411-22-3
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C17-H21-N.Cl-H
- MOLECULAR WEIGHT :
- 275.85
- WISWESSER LINE NOTATION :
- R1Y1&N1&1R &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 160 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 2,33,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 227 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 2,33,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 102 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 6,15,1964
Safety Information
[ Symbol ]:
GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H311-H331-H361
[ Precautionary Statements ]:
P261-P280-P301 + P310-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
T,F
[ Risk Phrases ]:
23/24/25-63-39/23/24/25-11
[ Safety Phrases ]:
22-36/37/39-45-36/37-16
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
SG9625000
[ HS Code ]:
2921499090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921499090
[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
J. Pharmacol. Exp. Ther. 243 , 955-962, (1987)
Rhesus monkeys were trained to discriminate intragastrically administered d-amphetamine (AMPH) or pentobarbital (PENTO) from saline using a signaled shock-avoidance trail procedure. All monkeys mainta...
Simultaneous analysis of benzphetamine and its metabolites, and quantitation of urinary p-hydroxy-N-benzylamphetamine by micellar electrokinetic chromatography.Biol. Pharm. Bull. 21 , 1207, (1998)
We developed a method for simultaneous analysis of benzphetamine (BZ) and its metabolites, p-hydroxy-N-benzylamphetamine (pHBA), p-hydroxybenzphetamine (pHBZ), amphetamine (AP), methamphetamine and p-...