D-Methamphetamine
Controlled Substances
Names
[ CAS No. ]:
537-46-2
[ Name ]:
D-Methamphetamine
[Synonym ]:
Phenethylamine, N,α-dimethyl-, (S)-(+)-
(2S)-N-Methyl-1-phenylpropan-2-amine
Methyl-β-phenylisopropylamine
Metamfetamine
(aS)-N,a-Dimethylbenzeneethanamine
Metamphetamine
L-Methamphetamine
d-N,α-Dimethylphenethylamine
Methylamphetamine
(+)-N,a-Dimethyl-b-phenylethylamine
(S)-(+)-N,a-Dimethylphenethylamine
(S)-(+)-Deoxyephedrine
Metanfetamina [inn-spanish]
(2S)-N-Methyl-1-phenyl-2-propanamine
d-Methamphetamine
d-Methylamphetamine
Norodin
S-(+)-Methamphetamine
Benzeneethanamine, N,α-dimethyl-, (S)-
d-Phenylisopropylmethylamine
Methamphetamine
d-deoxyephedrine
d-N-methylamphetamine
(+)-Methylamphetamine
Benzeneethanamine, N,α-dimethyl-, (αS)-
d-Desoxyephedrine
(+)-N,a-Dimethylphenethylamine
desohyephedrine
Methyl-b-phenylisopropylamine
(S)-Methylamphetamine
(+)-methamphetamine
(+)-N-Methylamphetamine
2S-(+)-Methamphetamine
(+)-(S)-Deoxyephedrine
d-N,a-Dimethylphenethylamine
(S)-N,a-Dimethylbenzeneethanamine
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
215.5±9.0 °C at 760 mmHg
[ Melting Point ]:
143°C (estimate)
[ Molecular Formula ]:
C10H15N
[ Molecular Weight ]:
149.233
[ Flash Point ]:
86.8±10.9 °C
[ Exact Mass ]:
149.120453
[ PSA ]:
12.03000
[ LogP ]:
1.94
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.503
[ Storage condition ]:
2-8°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SH4910000
- CHEMICAL NAME :
- Phenethylamine, N,alpha-dimethyl-, (S)-(+)-
- CAS REGISTRY NUMBER :
- 537-46-2
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C10-H15-N
- MOLECULAR WEIGHT :
- 149.26
- WISWESSER LINE NOTATION :
- 1MY1&1R -D
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 195,647,1940 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 14 mg/kg/7D-I
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - monoamine oxidase Biochemical - Metabolism (Intermediary) - effect on mitochondrial function
- REFERENCE :
- JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 45,79,1987 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 240 mg/kg
- SEX/DURATION :
- female 13-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
- REFERENCE :
- DABBBA Dissertation Abstracts International, B: The Sciences and Engineering. (University Microfilms International, 300 N. Zeeb Rd., Ann Arbor, MI 48106) V.30- 1969- Volume(issue)/page/year: 54,4003,1994
Safety Information
[ Symbol ]:
GHS02, GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H301 + H311 + H331-H370
[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311
[ Hazard Codes ]:
F,T
[ Risk Phrases ]:
11-23/24/25-39/23/24/25
[ Safety Phrases ]:
16-36/37-45
[ RIDADR ]:
UN 1851
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
2921499090
Customs
[ HS Code ]: 2921499090
[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%