5411-22-3

5411-22-3 structure

Name: benzphetamine hydrochloride
Chemical Name: benzphetamine hydrochloride
CAS Number: 5411-22-3
Molecular Formula: C₁₇H₂₂ClN
Molecular Weight: 275.81600
Catalog: API Nervous system medication Other nervous system medication
Create Date: 2018-09-27 22:15:45
Modify Date: 2024-01-10 07:44:42

Name	benzphetamine hydrochloride
Synonyms	Benzphetamine hydrchloride Benzphetaminhydrochlorid didrex Benzyl-methyl-((S)-1-methyl-2-phenyl-aethyl)-amin,Hydrochlorid (+)-Benzphetamine hydrochloride (2S)-N-benzyl-N-methyl-1-phenylpropan-2-amine hydrochloride benzyl-methyl-((S)-1-methyl-2-phenyl-ethyl)-amine,hydrochloride d-benzphetaminehydrochloride Benzphetamine Hydrochloride CIII (200 mg) BENZPHETAMINE HYDROCHLORIDE--DEA inapetyl (S)-BenzphetaMine Hydrochloride

Boiling Point	334.3ºC at 760mmHg
Melting Point	129-130°
Molecular Formula	C₁₇H₂₂ClN
Molecular Weight	275.81600
Flash Point	141.5ºC
Exact Mass	275.14400
PSA	3.24000
LogP	4.55160
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SG9625000

CHEMICAL NAME :: Phenethylamine, N-benzyl-N,alpha-dimethyl-, hydrochloride, (+)-

CAS REGISTRY NUMBER :: 5411-22-3

LAST UPDATED :: 199706

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C17-H21-N.Cl-H

MOLECULAR WEIGHT :: 275.85

WISWESSER LINE NOTATION :: R1Y1&N1&1R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 160 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 2,33,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 227 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 2,33,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 102 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 6,15,1964

Symbol	GHS06, GHS08
Signal Word	Danger
Hazard Statements	H301-H311-H331-H361
Precautionary Statements	P261-P280-P301 + P310-P311
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T,F
Risk Phrases	23/24/25-63-39/23/24/25-11
Safety Phrases	22-36/37/39-45-36/37-16
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	SG9625000
HS Code	2921499090

156-08-1

~99%

5411-22-3

Literature: Emcure Pharmaceuticals Limited Patent: US2011/46416 A1, 2011 ; Location in patent: Page/Page column 3 ;

100-44-7

51-57-0

~91%

5411-22-3

Literature: Pramanik, Chinmoy; Bapat, Kiran; Chaudhari, Ashok; Kulkarni, Mukund G.; Kolla, Rangarao; Sompalli, Srinivasarao; Tripathy, Narendra K.; Gurjar, Mukund K. Organic Process Research and Development, 2014 , vol. 18, # 4 p. 495 - 500

537-46-2

100-44-7

~97%

156-08-1

5411-22-3

Detail

Literature: MALLINCKRODT INC. Patent: WO2006/73547 A1, 2006 ; Location in patent: Page/Page column 7-8 ;

345-78-8

5411-22-3

152614-95-4

5411-22-3

Precursor 5
156-08-1 100-44-7 51-57-0 537-46-2
345-78-8
DownStream 0

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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