Hordenine

Names

[ CAS No. ]:
539-15-1

[ Name ]:
Hordenine

[Synonym ]:
4-[2-(Dimethylamino)ethyl]phenol
Cactine
Anhaline
Peyocactine
N,N-dimethyltyramine
Hordenin
Phenol, 4-[2-(dimethylamino)ethyl]-
Hordetin
Hordenine
p-[2-(Dimethylamino)ethyl]phenol
2-(4-Hydroxyphenyl)-N,N-dimethylethylamine (4-(2-Dimethylaminoethyl)phenol
MFCD00051462
p-Hydroxy-N,N-dimethylphenethylamine
4-(2-(Dimethylamino)ethyl)phenol
Ordenina
Eremursine
EINECS 222-740-5
Anhalin
Phenol, p-[2-(dimethylamino)ethyl]-
Ordenine
4-Hydroxy-N,N-dimethylphenethylamine
N,N-Dimethyl-p-hydroxyphenethylamine
Anhalin-d6
N,N-dimethyl-2-(4-hydroxyphenyl)ethylamine

Biological Activity

[Description]:

Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Kim SC, et al. Hordenine, a single compound produced during barley germination, inhibits melanogenesis in human melanocytes. Food Chem. 2013 Nov 1;141(1):174-81.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
270.2±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₅NO

[ Molecular Weight ]:
165.232

[ Flash Point ]:
123.5±21.3 °C

[ Exact Mass ]:
165.115356

[ PSA ]:
23.47000

[ LogP ]:
1.40

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.542

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H317-H319

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-36-43

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Development of immunoassays for tyramine and tryptamine toxins of Phalaris aquatica L.

J. Agric. Food Chem. 48(1) , 27-32, (2000)

The leaves of the perennial pasture grass Phalaris aquatica L. (phalaris) contain two groups of known toxins, indole alkaloids, primarily dimethyltryptamines and N-methyltyramines, which cause illness...

Some hematological and histopathological effects of the alkaloids gramine and hordenine on meadow voles (Microtus pennsylvanicus).

Toxicology 18(2) , 125-31, (1980)

Meadow voles (Microtus pennsylvanicus) were used to evaluate the relative toxicity of the alkaloids, gramine and hordenine, which are present in reed canarygrass (Phalaris arundinacea) and to assess t...

Rapid formation of N-nitrosodimethylamine from gramine, a naturally occurring precursor in barley malt.

IARC Sci. Publ. (57) , 337-46, (1984)

The two tertiary amine alkaloids, hordenine and gramine, which are biosynthesized in malt during germination, were subjected to nitrosation under conditions typical for the study of tertiary amine nit...