4-Methoxyphenylethylamine
Names
[ CAS No. ]:
55-81-2
[ Name ]:
4-Methoxyphenylethylamine
[Synonym ]:
4-Methoxyphenethylamine
MFCD00008192
EINECS 200-245-5
4-Methoxyphenylethylamine
2-(4-Methoxyphenyl)ethanamine
4-Methoxy-β-phenylethylamine
Benzeneethanamine, 4-methoxy-
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
255.2±0.0 °C at 760 mmHg
[ Melting Point ]:
249-251°C
[ Molecular Formula ]:
C9H13NO
[ Molecular Weight ]:
151.206
[ Flash Point ]:
105.3±13.6 °C
[ Exact Mass ]:
151.099716
[ PSA ]:
35.25000
[ LogP ]:
1.37
[ Appearance of Characters ]:
liquid | light yellow
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.526
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SH7875000
- CHEMICAL NAME :
- Phenethylamine, p-methoxy-
- CAS REGISTRY NUMBER :
- 55-81-2
- BEILSTEIN REFERENCE NO. :
- 0508967
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C9-H13-N-O
- MOLECULAR WEIGHT :
- 151.23
- WISWESSER LINE NOTATION :
- Z2R DO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7150 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1358 (estimated) No. of Female Employees: 956 (estimated)
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 2735 8/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
SH7875000
[ HS Code ]:
29222900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922299090
[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Biochemistry 40 , 14215, (2001)
Cytochrome P450 (P450) 2D6 oxidizes a wide variety of drugs typically at a distance of 5-7 A from a basic nitrogen on the substrate. To investigate the determinants of P450 2D6 catalysis, we analyzed ...
Electrochemical Investigation of oligonucleotide-DNA hybridization on poly(4-methoxyphenethylamine).Int. J. Mol. Sci. 9(7) , 1173-88, (2008)
This work describes the immobilization of purine and pyrimidine bases and immobilization/hybridization of synthetic oligonucleotides on graphite electrodes modified with poly(4-methoxyphenethylamine) ...
Selectivity of 4-methoxyphenethylamine derivatives as inhibitors of monoamine oxidase.J. Pharm. Sci. 65(10) , 1539-40, (1976)
It has been established that the oxidative deamination of tyramine by monoamine xodase is inhibited by (+/-)-4-methoxy-beta-hydroxyphenethylamine and its N-methylated derivatives. This particular seri...