UNII:87652943HP
Names
[ CAS No. ]:
529-33-9
[ Name ]:
UNII:87652943HP
[Synonym ]:
UNII:87652943HP
ac-α-Tetralol
MFCD00001739
1-Naphthalenol, 1,2,3,4-tetrahydro-
(R)-Tetralin-1-ol
Tetrahydro-1-naphthol
(R)-Tetrahydro-1-naphthol
EINECS 208-459-0
1,2,3,4-Tetrahydronaphthalen-1-ol
1,2,3,4-Tetrahydro-1-naphthalenol
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
254.8±0.0 °C at 760 mmHg
[ Melting Point ]:
28-104ºC
[ Molecular Formula ]:
C10H12O
[ Molecular Weight ]:
148.202
[ Flash Point ]:
99.9±11.0 °C
[ Exact Mass ]:
148.088821
[ PSA ]:
20.23000
[ LogP ]:
2.05
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.585
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QL5075000
- CHEMICAL NAME :
- 1-Naphthol, 1,2,3,4-tetrahydro-
- CAS REGISTRY NUMBER :
- 529-33-9
- BEILSTEIN REFERENCE NO. :
- 2046227
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C10-H12-O
- MOLECULAR WEIGHT :
- 148.22
- WISWESSER LINE NOTATION :
- L66&TJ GQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,217,1986
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,217,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1620 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 28,313,1974
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
QL5075000
[ HS Code ]:
29062900
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2907199090
[ Summary ]:
2907199090 other monophenols VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
J. Med. Chem. 45(25) , 5514-22, (2002)
Comparative Molecular Field Analysis (CoMFA) methods were used to produce a 3D-QSAR model that correlated the catalytic efficiency of rat hepatic aryl sulfotransferase (AST) IV, expressed as log(k(cat...
Metabolism of tetralin and toxicity of Cuprex in man.Drug Metab. Dispos. 1(3) , 577-9, (1973)
Influence of phenylalanines 77 and 138 on the stereospecificity of aryl sulfotransferase IV.
Drug Metab. Dispos. 32(5) , 559-65, (2004)
Aryl sulfotransferase (AST) IV (also named tyrosine-ester sulfotransferase and ST1A1) is a major phenol sulfotransferase in the rat, and it catalyzes the sulfation of many drugs, carcinogens, and othe...