(r)-(-)-1,2,3,4-tetrahydro-1-naphthol

Names

[ Name ]:
(r)-(-)-1,2,3,4-tetrahydro-1-naphthol

[Synonym ]:
(R)-(-)-α-Tetralol
(R)-(-)-1,2,3,4-Tetrahydro-1-naphthol
(R)-Tetralin-1-ol
24-Tetrahydro-1-naphthol
MFCD00063005
(R)-Tetralol
(-)-1-Naphthalenol
(R)-1-Tetralol
(R)-1,2,3,4-tetrahydro-naphthalen-1-ol
(R)-1,2,3,4-Tetrahydronaphthalen-1-ol

Chemical & Physical Properties

[ Density]:
1.09 g/mL at 25 °C(lit.)

[ Boiling Point ]:
140 °C17 mm Hg(lit.)

[ Melting Point ]:
37-39 °C

[ Molecular Formula ]:
C₁₀H₁₂O

[ Molecular Weight ]:
148.20200

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
148.08900

[ PSA ]:
20.23000

[ LogP ]:
2.05630

[ Vapour Pressure ]:
0.00874mmHg at 25°C

[ Index of Refraction ]:
1.584

[ Storage condition ]:
0-10°C

MSDS

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Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Preparation

Articles

Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17.

J. Med. Chem. 49 , 1818-27, (2006)

A set of 28 enantiomers comprising rigid and flexible secondary alcohols was synthesized by the asymmetric Corey-Bakshi-Shibata reduction. The enantiomerically pure alcohols were subjected to enzymati...