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Ibodutant

Names

[ CAS No. ]:
522664-63-7

[ Name ]:
Ibodutant

[Synonym ]:
Ibodutant
UNII-1H7RSQ28BJ

Biological Activity

[Description]:

MEN 15596 is a potent and selective tachykinin NK2 receptor antagonist with a pKi of 10.1.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor
Research Areas >> Neurological Disease

[Target]

pKi: 10.1 (Tachykinin NK2 receptor)[1]


[References]

[1]. Cialdai C, et al. MEN15596, a novel nonpeptide tachykinin NK2 receptor antagonist. Eur J Pharmacol. 2006 Nov 7;549(1-3):140-8.


[Related Small Molecules]

Substance P acetate salt | rolapitant | SB-222200 | Fezolinetant | Netupitant | [Sar9,Met(O2)11]-Substance P TFA | MLE-4901 | Succinyl-(Asp6,N-Me-Phe8)-Substance P (6-11) | Maropitant | NKP608 | Serlopitant | Talnetant | Y1 receptor antagonist 1 | [bAla8]-Neurokinin A(4-10)

Chemical & Physical Properties

[ Molecular Formula ]:
C37H48N4O4S

[ Molecular Weight ]:
644.86600

[ Exact Mass ]:
644.34000

[ PSA ]:
134.99000

[ LogP ]:
7.24400

Related Compounds

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