Vitamin D4

Names

[ CAS No. ]:
511-28-4

[ Name ]:
Vitamin D4

[Synonym ]:
EINECS 200-673-2
MFCD00078131
22,23-Dihydroergocalciferol
(3S,5Z,7E)-9,10-Secoergosta-5,7,10-trien-3-ol
(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5S)-5,6-dimethylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol

Biological Activity

[Description]:

Vitamin D4 is the active analogue of Vitamin D.

[Related Catalog]:

Signaling Pathways >> Vitamin D Related >> VD/VDR

Research Areas >> Metabolic Disease

[References]

[1]. Byford V, et al. Use of vitamin D(4) analogs to investigate differences in hepatic and target cell metabolism of vitamins D(2) and D(3). Biochim Biophys Acta. 2002 Jul 11;1583(2):151-66.

[2]. Tachibana Y, Tsuji M. Study on the metabolites of 1alpha,25-dihydroxyvitamin D4. Steroids. 2001 Feb;66(2):93-97.

[3]. Tsugawa N, et al. Biological activity profiles of 1alpha,25-dihydroxyvitamin D2, D3, D4, D7, and 24-epi-1alpha,25-dihydroxyvitamin D2. Biol Pharm Bull. 1999 Apr;22(4):371-7.

[4]. Rikkers H, DeLuca H, Lobeck C. Metabolism and serum protein binding of 3H-vitamin D4 in vitamin D-resistant rickets. J Pediatr. 1969 May;74(5):828.

[5]. De Luca HF, Weller M, Blunt JW, Neville PF. Synthesis, biological activity., and metabolism of 22,23-3H vitamin D4. Arch Biochem Biophys. 1968 Mar 20;124(1):122-8.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
0.96 g/cm3

[ Boiling Point ]:
504.9ºC at 760 mmHg

[ Melting Point ]:
96-98ºC

[ Molecular Formula ]:
C₂₈H₄₆O

[ Molecular Weight ]:
398.66400

[ Flash Point ]:
219.2ºC

[ Exact Mass ]:
398.35500

[ PSA ]:
20.23000

[ LogP ]:
7.86500

[ Index of Refraction ]:
1.52

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
T+: Very toxic;

[ Risk Phrases ]:
24/25-26-48/25

[ Safety Phrases ]:
28-36/37

[ RIDADR ]:
UN 2811 6.1/PG 2

[ WGK Germany ]:
2

[ RTECS ]:
VS2900000

[ HS Code ]:
2936240000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2936240000