Aminopyrazine

Names

[ Name ]:
Aminopyrazine

[Synonym ]:
Aminopyrazine
3-aminopyrazine
2-AMINOPYRAZINE
Pyrazinamine
Pyrazin-2-amin
2-Pyrazinamine
Pyrazin-2-Amine
EINECS 225-748-7
MFCD00006137

Biological Activity

[Description]:

Pyrazinamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

[In Vitro]

2-Aminopyrazine 是一种可用于药物合成的合成中间体。

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
250.9±20.0 °C at 760 mmHg

[ Melting Point ]:
118-120 °C(lit.)

[ Molecular Formula ]:
C₄H₅N₃

[ Molecular Weight ]:
95.10

[ Flash Point ]:
129.1±9.0 °C

[ Exact Mass ]:
95.048347

[ PSA ]:
51.80000

[ LogP ]:
0.15

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.598

[ Storage condition ]:
Flammables area

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
F:Flammable

[ Risk Phrases ]:
R11;R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Distribution study of atorvastatin and its metabolites in rat tissues using combined information from UHPLC/MS and MALDI-Orbitrap-MS imaging.

Anal. Bioanal. Chem 406(19) , 4601-10, (2014)

The combination of ultrahigh-resolution mass spectrometry imaging (UHRMSI) and ultrahigh-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC/MS/MS) was used for the identifi...

In vitro and in vivo activities of 2-aminopyrazines and 2-aminopyridines in experimental models of human African trypanosomiasis.

Antimicrob. Agents Chemother. 57(2) , 1012-8, (2013)

New drugs for the treatment of human African trypanosomiasis are urgently needed. A number of 2-aminopyrazines/2-aminopyridines were identified as promising leads following a focused screen of 5,500 c...

Chemistry around imidazopyrazine and ibuprofen: discovery of novel fatty acid amide hydrolase (FAAH) inhibitors.

Eur. J. Med. Chem. 45 , 3564-74, (2010)

Based on the imidazo-[1,2-a]-pyrazin-3-(7H)-one scaffold, a dual action prodrug has been designed for combining antioxidant and anti-inflammatory activities, possibly unmasked upon oxidation. The cons...