2-Chloropyrazine

Names

[ Name ]:
2-Chloropyrazine

[Synonym ]:
2-Chloro-pyrazine
2-chloropyrazin
2-Dichloropyrazine
Pyrazine,chloro
Pyrazine, 2-chloro-
2-chloro-1,4-pyrazine
2-Chloro-1,4-diazine
chloro-pyrazin
EINECS 238-517-0
MFCD00006124
Chloropyrazine
pyrazine chloride
2-Cl-pyrazine
CHLOROPYRAZINE,2

Biological Activity

[Description]:

Chloropyrazine (Pyrazin-2-yl chloride) is a member of pyrazines, can be used for the synthesis of active compounds[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Mosrin M, et al. Regio- and chemoselective multiple functionalization of chloropyrazine derivatives. Application to the synthesis of coelenterazine. Org Lett. 2009 Aug 6;11(15):3406-9.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
155.3±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄H₃ClN₂

[ Molecular Weight ]:
114.533

[ Flash Point ]:
57.8±0.0 °C

[ Exact Mass ]:
113.998474

[ PSA ]:
25.78000

[ LogP ]:
0.64

[ Vapour Pressure ]:
3.9±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.535

[ Water Solubility ]:
INSOLUBLE

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
29339990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Cobalt-catalyzed cross-coupling between in situ prepared arylzinc halides and 2-chloropyrimidine or 2-chloropyrazine.

J. Org. Chem. 74(8) , 3221-4, (2009)

A cobalt-catalyzed cross-coupling of aryl halides with 2-chloropyrimidines or 2-chloropyrazines is reported in satisfactory to high yields. The key step of this procedure is the formation of aromatic ...

Gas chromatographic assay for the new antitumor agent pyrazine-2-diazohydroxide (diazohydroxide) and its stability in buffer, blood and plasma.

J. Chromatogr. A. 383(1) , 77-83, (1986)

Diazohydroxide is a new antitumor agent being considered for clinical trial. A sensitive and specific assay for diazohydroxide in physiological media, plasma and blood has been developed based on conv...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.