Harmol

Names

[ CAS No. ]:
487-03-6

[ Name ]:
Harmol

[Synonym ]:
1-Methyl-9H-pyrido[3,4-b]indol-7-ol
7-HYDROXY-1-METHYL-9H-PYRIDO[3,4-B]INDOLE
1-methyl-9H-pyrido[3,4-b]indol-7-ol
METHYLPYRIDOINDOLOL

Biological Activity

[Description]:

Harmol categorized as a β-carboline alkaloid. Harmol is a potent MAO inhibitor used as an analytical reference standard[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase

Research Areas >> Neurological Disease

[References]

[1]. Blei F, et al. Simultaneous Production of Psilocybin and a Cocktail of β-Carboline Monoamine Oxidase Inhibitors in "Magic" Mushrooms. Chemistry. 2020 Jan 13;26(3):729-734.

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Boiling Point ]:
552.7ºC at 760mmHg

[ Melting Point ]:
231ºC

[ Molecular Formula ]:
C₁₂H₁₀N₂O

[ Molecular Weight ]:
198.22100

[ Flash Point ]:
255ºC

[ Exact Mass ]:
198.07900

[ PSA ]:
48.91000

[ LogP ]:
2.73010

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.794

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22

[ Safety Phrases ]:
36

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%